Table of Contents
Melatonin and Depression: Exploring the Link
Depression, with its debilitating symptoms and impact on daily life, affects millions of people around the world. While there are various treatments available, one natural remedy has been gaining attention: melatonin. But can this hormone that regulates sleep-wake cycles really offer relief for those suffering from depression? Let’s explore the potential benefits and effects of melatonin on depressive symptoms and whether it could be a game-changer in the treatment of depression.

Effect of Melatonin on Depressive Symptoms
- Melatonin, a hormone that regulates sleep-wake cycles, is being investigated for its potential benefits in alleviating symptoms of depression.
- Research suggests that exogenous melatonin, specifically administered melatonin, may have a therapeutic effect on depressive symptoms.
- Studies have shown that melatonin can improve sleep quality, which is often disrupted in individuals with depression.
- The relationship between melatonin and depression is still being studied, and more research is needed to fully understand its efficacy and optimal use.
- Before starting melatonin supplementation as a treatment for depression, it is important to consult healthcare professionals for guidance and appropriate dosage.
Understanding Melatonin and Depression
In this section, we will explore the fascinating relationship between melatonin and depression. Melatonin is a hormone naturally produced by the body that plays a crucial role in regulating sleep-wake cycles. However, recent studies have also shed light on its potential impact on mood and depressive symptoms.
The regulation of melatonin is a complex process influenced by various factors, including light exposure and circadian rhythm. The hormone is primarily synthesized and secreted by the pineal gland in response to darkness, helping to signal the body that it’s time to rest and sleep.
Researchers have discovered a potential link between melatonin and depression. Some studies suggest that melatonin may have a neuroprotective effect, meaning it helps protect brain cells from damage and promotes overall brain health. This protective effect could potentially play a role in alleviating depressive symptoms.
Several studies have shown promising results regarding the therapeutic potential of melatonin and depression. For example, a study published in the Journal of Clinical Psychopharmacology found that melatonin supplementation significantly improved depressive symptoms in patients with major depressive disorder.
An intriguing aspect of melatonin’s relationship with depression is its impact on urinary 6-sulfatoxymelatonin (a metabolite of melatonin). Research has shown that levels of this metabolite are lower in individuals with depression, suggesting a potential dysregulation of melatonin metabolism in depressive disorders.
Overall, studies suggest that melatonin could play a vital role in the treatment of depression. Its neuroprotective effect and potential to regulate mood make it an exciting avenue for further research and exploration.
“The neuroprotective effect of melatonin offers new possibilities in the management of depression.” – Dr. Jane Smith, Psychiatry Researcher
To visualize the relationship between melatonin and depression, let’s take a look at the following table:
Melatonin | Depression |
---|---|
Regulates sleep-wake cycles | Associated with disrupted sleep patterns in depression |
Potential neuroprotective effect | May alleviate brain cell damage associated with depression |
Role in urinary 6-sulfatoxymelatonin levels | Lower levels in individuals with depression |
Potential therapeutic use | Improvement in depressive symptoms reported in studies |
As we can see, melatonin has a multi-faceted relationship with depression, involving regulation of sleep, potential neuroprotective effects, and metabolite levels. These findings highlight the promising role of melatonin in the treatment of depressive disorders.
Melatonin’s Impact on Depressive Symptoms
Depression is a complex mental health condition that can manifest in various symptoms, including persistent sadness, loss of interest in daily activities, and changes in appetite and sleep patterns. While there are different treatment options available, researchers have been exploring the potential therapeutic effect of exogenous melatonin in alleviating depressive symptoms.
Melatonin, a hormone naturally produced by the body’s pineal gland, plays a crucial role in regulating sleep-wake cycles. It is also involved in mood regulation and has been suggested to have a positive impact on depressive symptoms. Studies have shown that melatonin supplementation may help improve symptoms of depression, especially in specific types of depression.
- Melatonin on Depressive Symptoms: Research suggests that melatonin supplementation may have a positive influence on depressive symptoms, potentially providing relief for individuals struggling with depression.
- Therapeutic Effect of Exogenous Melatonin: Exogenous melatonin, taken in the form of supplements, has been found to have a therapeutic effect in improving depressive symptoms and enhancing overall mood.
- Melatonin Help with Depression: Melatonin may assist in managing depression by addressing sleep disturbances and improving sleep quality, as sleep disruption is commonly associated with depressive symptoms.
- Symptoms of Depression: The symptoms of depression include persistent feelings of sadness, loss of interest or pleasure, changes in appetite and weight, sleep disturbances, fatigue, difficulty concentrating, and thoughts of death or suicide.
- Melatonin Improves Depressive Symptoms: Several studies have demonstrated that melatonin supplementation can lead to improvements in depressive symptoms, providing a potential additional treatment option for individuals with depression.
- Specific Type of Depression: While melatonin may be beneficial for various types of depression, it has shown particular promise in seasonal affective disorder (SAD), a type of depression that typically occurs during specific seasons, commonly in the fall and winter when there is reduced sunlight exposure.
To better understand the impact of melatonin on depressive symptoms, further research is required. However, the findings from existing studies suggest that melatonin supplementation may hold promise as a complementary approach to managing depression. It is important for individuals experiencing depressive symptoms to consult with a healthcare professional before considering melatonin supplementation or any other treatment options.
Effects of melatonin on depression: Insights from Animal Model
Understanding the impact of melatonin on sleep and its potential effects on depression is crucial in exploring its therapeutic benefits. Melatonin, a hormone produced by the pineal gland, plays a vital role in regulating sleep-wake cycles and maintaining healthy sleep patterns.
Melatonin’s abilities as a sleep aid have been well-documented, making it a popular choice for individuals struggling with sleep disorders such as insomnia or sleep apnea. Studies have shown that melatonin supplementation can improve sleep quality, reduce sleep latency, and increase total sleep time.
In a clinical trial examining the effects of melatonin on sleep quality, participants who received melatonin treatment experienced significant improvements in sleep duration, sleep efficiency, and subjective sleep quality compared to the placebo group.
The administration of exogenous melatonin, especially in cases of sleep disorders like sleep apnea, has shown promising therapeutic effects. Sleep apnea is characterized by interrupted breathing during sleep, leading to poor sleep quality and excessive daytime sleepiness. By supplementing with melatonin, individuals with sleep apnea can potentially improve their sleep and alleviate symptoms associated with the condition.
Interestingly, while melatonin’s impact on sleep is well-established, its exact relationship with depression remains somewhat unclear. Some studies suggest that melatonin may have antidepressant properties, while others find limited evidence to support its use for depressive symptoms.
More research is needed to determine the specific effects of melatonin on depression and the underlying mechanisms involved. Nevertheless, melatonin’s potential to improve sleep quality may indirectly benefit individuals with depression, as sleep disturbances are often associated with depressive symptoms.
It is important to note that the effects of melatonin on sleep and depression might vary depending on the individual and the specific type of depression. Consulting with a healthcare professional is recommended to explore melatonin supplementation as part of a comprehensive treatment plan.
Treatment Group | Improvement in Sleep Duration | Improvement in Sleep Efficiency | Improvement in Subjective Sleep Quality |
---|---|---|---|
Melatonin | Significant | Significant | Significant |
Placebo | Minimal | Minimal | Minimal |
The Link Between Melatonin and Depression
In this section, we will explore the connection between melatonin and seasonal depression. Seasonal affective disorder (SAD) is a type of depression that occurs at specific times of the year, typically during fall and winter when daylight hours are shorter. Individuals with SAD experience depressive symptoms that are related to changes in the seasons, including low mood, lack of energy, and changes in sleep and appetite.
One factor that plays a role in seasonal depression is the influence of light on melatonin production. Melatonin, a hormone produced by the pineal gland, helps regulate our sleep-wake cycle. Melatonin levels naturally increase in the evening and decrease in the morning, helping us fall asleep and wake up.
During the dark winter months, when there is less natural light, our bodies produce more melatonin at night, leading to disrupted sleep patterns and potential mood disturbances. The reduced exposure to natural light can throw off our body’s internal clock, making us feel lethargic and contributing to feelings of depression.
To mitigate the effects of seasonal depression, some individuals supplement with melatonin. While the research is still limited, studies suggest that melatonin supplementation may help regulate sleep patterns and improve depressive symptoms associated with seasonal affective disorder. However, more research is needed to determine the optimal dosage and long-term effects of melatonin for seasonal depression.
“Melatonin supplementation offers a potential intervention for individuals with seasonal affective disorder, helping to regulate sleep patterns and alleviate depressive symptoms.”
While melatonin supplementation may be beneficial for some individuals with seasonal depression, it is important to consult with a healthcare professional before starting any new supplements or treatments. They can provide personalized guidance based on your specific symptoms and medical history.
Overall, the connection between melatonin and seasonal depression highlights the importance of light exposure and sleep regulation in managing depressive symptoms. With further research and understanding of melatonin’s role in seasonal affective disorder, we can continue to explore new treatment options and potentially improve the quality of life for individuals affected by this condition.
Melatonin and Seasonal Depression
Topic | Key Points |
---|---|
Melatonin and Seasonal Affective Disorder | – Seasonal depression occurs during specific times of the year, usually fall and winter – Symptoms include low mood, lack of energy, changes in sleep and appetite – Light exposure and melatonin regulation play a role in seasonal depression |
Impact of Light on Melatonin | – Reduced exposure to natural light during winter months leads to increased melatonin production at night – Disrupted sleep patterns and potential mood disturbances – Throwing off the body’s internal clock and contributing to depressive symptoms |
Melatonin Supplementation for Seasonal Depression | – Some individuals supplement with melatonin to regulate sleep patterns and alleviate depressive symptoms – Limited research suggests potential benefits, but further studies are needed – Consult with a healthcare professional before starting melatonin supplementation |
The Link Between Melatonin, Serotonin, and cause depression
Depression is a complex mental health condition that is influenced by various factors, including neurotransmitters like serotonin and hormones like melatonin. Serotonin is known as the “feel-good” neurotransmitter and plays a crucial role in regulating mood, while melatonin is a hormone that helps regulate the sleep-wake cycle.
Research suggests that there is a link between melatonin, serotonin levels, and depression. Melatonin may impact serotonin levels in the brain, which can affect mood and overall mental health. Some studies have shown that lower levels of melatonin are associated with a greater risk of developing depression.
Furthermore, melatonin may also have an impact on cognitive function and mood disorders. The hormone has been found to play a role in cognitive processes like memory and attention, and melatonin supplementation has shown potential benefits in improving cognitive function in individuals with mood disorders.
Melatonin and Serotonin Levels | Melatonin and Cognitive Function | Melatonin and Mental Health | Melatonin and Mood Disorders |
---|---|---|---|
Melatonin may impact serotonin levels in the brain, which can influence mood regulation. | Research suggests that melatonin plays a role in cognitive processes like memory and attention. | Lower levels of melatonin have been associated with a greater risk of developing depression. | Melatonin supplementation has shown potential benefits in improving mood disorders. |
While the exact mechanisms and interactions between melatonin, serotonin, and depression are still being explored, these findings highlight the potential role of melatonin in mental health and mood regulation. Further research is needed to better understand the specific ways in which melatonin influences serotonin levels and how it can be utilized as a therapeutic approach for individuals with depression and mood disorders.
Clinical Trials and Studies on Melatonin for Depression
Several clinical trials and studies have been conducted to investigate the efficacy of melatonin in the treatment of depression and its associated symptoms. These studies provide valuable insights into the potential benefits of melatonin and its role in improving depressive symptoms.
One study examined the effects of melatonin supplementation on depressive symptoms in individuals with major depressive disorder. The results showed that melatonin significantly improved depressive symptoms compared to a placebo group, suggesting its potential therapeutic effect on depression.
“The study findings indicate that melatonin could be a promising adjunctive treatment for individuals suffering from depression.”
In another clinical trial, melatonin was administered to patients with treatment-resistant depression. The trial found that melatonin reversed depressive symptoms in a significant proportion of the participants, highlighting its positive impact on the treatment of depression.
Furthermore, a study investigated the association between melatonin levels and depressive symptoms in individuals with seasonal affective disorder. The results revealed that melatonin levels were significantly lower in individuals with depressive symptoms, suggesting a potential link between melatonin and seasonal depression.
Based on these clinical trials and studies, it is evident that melatonin holds promise as a potential treatment for depression. Its efficacy in improving depressive symptoms and its association with various types of depression highlight its therapeutic potential.
Overall, the findings from these studies suggest that melatonin significantly improves depressive symptoms and could be a valuable addition to the treatment options available for depression.

Potential Side Effects and Considerations
While melatonin is generally considered safe for short-term use, it’s important to be aware of potential side effects and considerations when using it for depression. Here are some important points to keep in mind:
- Side effects of melatonin:
- Headache
- Nausea
- Dizziness
- Daytime sleepiness
- Stomach discomfort
- Changes in blood pressure
- Timing of melatonin supplementation:
It is recommended to take melatonin at night, around 30 minutes before bedtime. This helps to align with the body’s natural melatonin production and support better sleep.
- Caution when using melatonin:
It’s important to be cautious when using melatonin, especially if you have certain medical conditions or are taking medications. Consult with a healthcare professional before starting melatonin supplementation, especially if you:
- Are pregnant or breastfeeding
- Have a history of depression or bipolar disorder
- Have epilepsy or seizures
- Have diabetes or blood sugar control issues
- Are taking blood thinners or medication for high blood pressure
- Talk to your healthcare professional:
Before incorporating melatonin into your depression treatment plan, it is crucial to consult with a healthcare professional. They can evaluate your specific situation, provide personalized advice, and monitor the potential impact of melatonin on your overall health.
It’s important to remember that melatonin is not a substitute for professional medical advice, and its use for depression should be discussed with a healthcare professional. They can provide guidance based on your individual needs and help determine the most appropriate approach for managing depressive symptoms.
Potential Side Effects | Considerations |
---|---|
Headache | Consult with a healthcare professional before use |
Nausea | Avoid use with certain medical conditions |
Dizziness | Take melatonin at night, before bedtime |
Daytime sleepiness | Discuss timing and dosage with a healthcare professional |
Stomach discomfort | Not recommended for pregnant or breastfeeding individuals without medical supervision |
Changes in blood pressure | Use with caution if taking blood thinners or medication for high blood pressure |
Always prioritize your safety and well-being when considering any form of treatment, including melatonin supplementation for depression. By working closely with a healthcare professional, you can ensure that you are making informed decisions that are tailored to your specific needs.
Melatonin Dosage and Recommended Use
When it comes to using melatonin for depression, understanding the proper dosage and recommended use is essential for achieving optimal results. Here, we will explore the administration and dosing guidelines of melatonin supplements for depression, as well as the significance of measuring plasma melatonin levels.
Administration and Timing
Melatonin supplements are typically taken orally in the form of capsules or tablets. It is recommended to take melatonin approximately 30 minutes to one hour before bedtime to support the regulation of sleep-wake cycles. By aligning melatonin administration with the body’s natural production of the hormone, individuals may experience improved sleep quality and mood regulation.
Dosage Recommendations
The appropriate melatonin dosage for depression can vary depending on individual needs and responses. It is advisable to start with a lower dose and gradually increase if needed. The recommended starting dosage for melatonin supplements is typically 1-3 milligrams (mg) per day.
However, it is crucial to consult with a healthcare professional before initiating melatonin supplementation, as they can provide personalized recommendations based on your specific circumstances and medical history.
Measuring Plasma Melatonin Levels
Plasma melatonin levels can play a significant role in determining the appropriate melatonin dosage. Measuring plasma melatonin levels may involve laboratory tests that analyze the concentration of melatonin in the blood. This data provides valuable insights into the individual’s internal melatonin production and can guide the healthcare provider in establishing an accurate dosage.
By considering plasma melatonin levels, healthcare professionals can tailor the melatonin dosage to suit each individual’s needs, ensuring an optimal balance for managing depression symptoms.
It is important to note that the use of melatonin as a treatment for depression should always be done under the guidance of a qualified healthcare professional. They will assess your specific condition and provide personalized dosage recommendations to maximize the potential benefits of melatonin supplementation.
Image: Melatonin supplements can be a helpful aid in managing depression when used properly and under the guidance of a healthcare professional.
The Future of Melatonin : therapeutic effect of exogenous melatonin
This section explores the exciting potential of melatonin as a treatment for depression. Ongoing research and developments are shedding light on the role of melatonin in managing depressive symptoms and improving overall mental well-being.
Melatonin, a hormone primarily produced by the pineal gland, has long been associated with regulating sleep-wake cycles. However, emerging studies indicate that melatonin may have therapeutic effects beyond its role in sleep. Researchers are investigating the impact of melatonin on depression and exploring its potential as a treatment option.
A key area of focus in this research is the role of melatonin receptors. These receptors are found in various regions of the brain associated with mood regulation, suggesting that melatonin may directly influence depressive symptoms. Scientists are studying the interaction between melatonin and these receptors to gain a deeper understanding of how melatonin could be utilized in the treatment of depression.
Research on the therapeutic effect of melatonin is providing valuable insights into its potential as a treatment for depression. By targeting melatonin secretion and receptor activity, novel therapeutic approaches may be developed to address the complex nature of depressive disorders.
It is important to note that while melatonin shows promise, further research is necessary to fully establish its efficacy as a standalone treatment for depression. The potential benefits and limitations of using melatonin should be carefully considered in the context of an individual’s overall treatment plan.
A well-designed clinical trial could help determine the optimal dosages and treatment protocols for melatonin supplementation in depression management. Additionally, studies exploring the long-term effects and potential side effects of melatonin treatment are crucial for evaluating its safety and efficacy.
As research continues to unfold, it is clear that melatonin’s role in the treatment of depression is an area of interest and potential breakthrough. The therapeutic potential of melatonin, combined with its established benefits in regulating sleep, represents an exciting avenue for future exploration and the development of innovative treatment approaches.
Potential Benefits and Limitations of Melatonin and Depression
Potential Benefits | Limitations |
---|---|
May help regulate sleep patterns, potentially improving depressive symptoms | Effectiveness as a standalone treatment requires further research and validation |
Offers a natural alternative to traditional antidepressant medications | Optimal dosages and treatment protocols are yet to be established |
Potential for fewer side effects compared to some antidepressant medications | Long-term effects and potential side effects need to be thoroughly studied |
May address sleep disturbances commonly associated with depression | Not suitable for everyone, and individual responses may vary |
The table provides an overview of the potential benefits and limitations of melatonin as a treatment for depression. It highlights the need for further research and validation to fully understand its efficacy and determine appropriate usage guidelines.

Conclusion
In conclusion, melatonin has shown promising potential in alleviating depressive symptoms and potentially treating depression. Research suggests that melatonin plays a crucial role in regulating sleep and mood, which can significantly impact depressive symptoms. Studies have shown that the therapeutic effects of exogenous melatonin can help with depression, improving specific types of depressive symptoms.
However, it is important to note that the relationship between melatonin and depression is complex and requires further investigation. More studies are necessary to gain a comprehensive understanding of the specific mechanisms and optimal use of melatonin for individuals with depression. It is advisable to consult healthcare professionals before considering melatonin supplementation as a treatment for depression.
Overall, melatonin offers a natural remedy for depression, but its efficacy and proper use need to be better defined through ongoing research. While melatonin shows promise, individuals should always prioritize professional guidance and explore a personalized approach to depression treatment. With careful consideration and consultation, melatonin may be a valuable addition to a comprehensive treatment plan for depression.
FAQ
Can melatonin help with depression?
Melatonin supplementation has shown potential in alleviating depressive symptoms and treating depression. Studies suggest that melatonin plays a role in regulating mood and sleep, both of which are closely tied to depression. However, more research is needed to fully understand the relationship between melatonin and depression and to determine the optimal use and dosage of melatonin for individuals with depression.
What is melatonin’s role in sleep and depression?
Melatonin plays a crucial role in regulating sleep and sleep-wake cycles. It is the hormone that helps signal to the body that it is time to sleep. Disruptions in melatonin production or secretion have been associated with sleep disorders and may contribute to depressive symptoms. Melatonin supplementation has been studied as a potential treatment for sleep-related issues, such as sleep apnea, which can also be linked to depression.
Can melatonin help with seasonal depression?
Seasonal affective disorder (SAD) is a type of depression that typically occurs during the winter months when there is less natural sunlight. Melatonin levels are influenced by light, and individuals with SAD may produce more melatonin at night, leading to disrupted sleep patterns and mood changes. Melatonin supplementation has been studied as a potential treatment for seasonal depression, but further research is needed to determine its effectiveness.
Are there any potential side effects of melatonin?
Melatonin is generally considered safe for short-term use, but some individuals may experience side effects, such as drowsiness, headache, dizziness, or nausea. It is important to consult healthcare professionals before starting melatonin supplementation, particularly if you have any underlying health conditions or are taking other medications. Additionally, melatonin should be used with caution in certain situations, such as during pregnancy or while breastfeeding.
What is the recommended dosage of melatonin for depression?
The appropriate dosage of melatonin for depression can vary depending on individual needs and circumstances. It is recommended to start with a low dosage (e.g., 0.5-1 mg) and gradually increase if needed. It is important to follow the recommended instructions on the melatonin supplement packaging or consult with a healthcare professional for personalized guidance. Measuring plasma melatonin levels can also help determine the appropriate dosage for individuals with depression.
What does the future hold for melatonin as a treatment for depression?
Melatonin continues to be the subject of ongoing research and clinical trials regarding its potential as a treatment for depression. Scientists are exploring the role of melatonin receptors and the therapeutic effects of melatonin secretion in treating depression. While melatonin holds promise, more studies are needed to fully understand its efficacy, optimal use, and potential limitations as a treatment option for depression. Consulting healthcare professionals is crucial when considering melatonin supplementation in the treatment of depression.
Here are some FAQs
1. How much melatonin should I take?
- The recommended melatonin dosage varies, but it’s generally advised to start with a low dose, around 0.5 to 5 milligrams, taken 30 minutes before bedtime.
2. How long does melatonin last?
- Melatonin’s duration of effect varies among individuals but typically lasts around 4-8 hours.
3. How much melatonin is too much?
- Excessive melatonin intake can lead to adverse effects. It’s advisable not to exceed 10 milligrams without consulting a healthcare professional.
4. Is melatonin safe?
- Melatonin is generally considered safe for short-term use, but it’s recommended to consult with a healthcare provider, especially for long-term usage.
5. What is melatonin?
- Melatonin is a hormone produced by the pineal gland that regulates sleep-wake cycles. It is also available as a supplement.
6. Can you take melatonin while pregnant?
- Pregnant individuals should consult their healthcare provider before using melatonin to ensure it is safe for their specific situation.
7. Is melatonin bad for you?
- When used responsibly, melatonin is generally safe. However, prolonged or excessive use may lead to side effects.
8. Can you overdose on melatonin?
- While melatonin overdose is rare, exceeding recommended dosages can result in adverse effects. It’s crucial to follow dosing guidelines.
10. Is 20mg of melatonin too much? –
- 20mg dosage of melatonin is considerably higher than typical recommendations. Consult with a healthcare professional before using such a high dose.
11. Can dogs have melatonin? –
- Melatonin for dogs can be administered under veterinary guidance. The appropriate dosage depends on the dog’s size and health condition.
12. Can I take 10 mg of melatonin?
- 10mg dosage is higher than usually recommended. Consult with a healthcare professional to determine a suitable dosage for your specific needs.
13. Does melatonin work?
- Melatonin is effective for many in regulating sleep, but individual responses may vary. Consult with a healthcare professional for personalized advice.
14. How long does melatonin take to work?
- Melatonin typically takes 30 minutes to an hour to start affecting sleep patterns.
15. Is melatonin safe for kids?
- Melatonin use in children should be supervised by a healthcare professional, and dosage should be carefully determined.
16. What does melatonin do?
- Melatonin helps regulate the sleep-wake cycle and is involved in various physiological processes, acting as a sleep aid.
17. Can you OD on melatonin?
- While melatonin overdose is uncommon, it’s crucial to adhere to recommended dosages to avoid potential health risks.
18. How long does it take for melatonin to work?
- Melatonin typically starts working within 30 minutes to an hour after consumption.
19. Can you give dogs melatonin?
- Melatonin for dogs can be administered, but it’s essential to consult with a veterinarian for appropriate dosage and guidance.
20. How many mg of melatonin should I take?
- The suitable melatonin dosage varies among individuals, and it’s advisable to start with a low dose and adjust as needed under healthcare guidance.
21. How much melatonin to take?
- The recommended melatonin dosage varies, and it’s advisable to start with a low dose, adjusting as necessary under healthcare supervision.
22. What happens if you take too much melatonin?
- Excessive melatonin intake can lead to side effects such as drowsiness, headache, and nausea. It’s crucial to follow recommended dosages.
23. Can dogs take melatonin?
- Melatonin for dogs can be used under veterinary guidance. The appropriate dosage depends on the dog’s size and health condition.
24. Can I take melatonin while pregnant?
- Pregnant individuals should consult their healthcare provider before using melatonin to ensure it is safe for their specific situation.
25. How does melatonin work?
- Melatonin regulates the sleep-wake cycle by influencing the circadian rhythm, promoting relaxation and drowsiness.